Last update: Sept. 4, 2014

Arformoterol

Low Risk for breastfeeding


Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.

Long-acting bronchodilator.

Its high molecular weight and plasma protein binding make excretion into breast milk unlikely

Terbutaline which is a related medication is excreted insignificantly in breast milk.

Plasma levels after inhalation of Salmeterol which is a related drug are insignificant.

Inhaled medication should of choice because a lower dose and fewer excretion into breast milk.

Alternatives

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Group

Arformoterol belongs to this group or family:

Pharmacokinetics

Variable Value Unit
Molecular weight 495 daltons
Protein Binding 52 - 65 %
Tmax 0,5 hours
T1/2 26 hours

References

  1. Sunovion Pharmaceuticals Inc Arformoterol Data Sheet 2012 Full text (in our servers)
  2. National Asthma Education and Prevention Program Asthma and Pregnancy Working Group. Managing asthma during pregnancy: recommendations for pharmacologic treatment-2004 update. 2004;1-57. 2004 Full text (link to original source) Full text (in our servers)
  3. Nelson-Piercy C. Asthma in pregnancy. Thorax. 2001 Abstract Full text (link to original source) Full text (in our servers)
  4. McDonald CF, Burdon JG. Asthma in pregnancy and lactation. A position paper for the Thoracic Society of Australia and New Zealand. Med J Aust. 1996 Abstract
  5. Ellsworth A. Pharmacotherapy of asthma while breastfeeding. J Hum Lact. 1994 Abstract
  6. Lindberg C, Boréus LO, de Château P, Lindström B, Lönnerholm G, Nyberg L. Transfer of terbutaline into breast milk. Eur J Respir Dis Suppl. 1984 Abstract
  7. Lönnerholm G, Lindström B. Terbutaline excretion into breast milk. Br J Clin Pharmacol. 1982 Abstract Full text (link to original source) Full text (in our servers)
  8. Boréus LO, de Château PU. Terbutaline in breast milk. Br J Clin Pharmacol. 1982 Abstract Full text (link to original source) Full text (in our servers)

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