Last update: April 24, 2014

Acetohexamide

Low Risk for breastfeeding


Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.

Sulfonilurea drugs stimulate secretion of endogen insulin.

Oral anti-diabetic drugs are useless for treatment of diabetes type 1. For diabetes type 2, diet and exercise are advisable. Breastfeeding helps to lower serum glucose level. See section on Maternal diabetes mellitus

Alternatives

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Tradenames

Main tradenames from several countries containing Acetohexamide in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 90 %
Molecular weight 324 daltons
Protein Binding 65 %
VD 0,2 l/Kg
Tmax 5 hours
T1/2 6 hours

References

  1. Berlin CM, Briggs GG. Drugs and chemicals in human milk. Semin Fetal Neonatal Med. 2005 Abstract
  2. Everett JA. Use of oral antidiabetic agents during breastfeeding. J Hum Lact. 1997 Abstract
  3. Moiel RH, Ryan JR. Tolbutamide orinase in human breast milk. Clin Pediatr (Phila). 1967 Abstract

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