Last update: Dec. 13, 2019
Minimal risk for breastfeeding and infant.
Progestogen used as an emergency contraceptive for use up to 72 hours postcoitus.
Oral administration in an isolated dose of 1.5 mg (several times higher than that used as a daily contraceptive).
It binds extensively to plasma proteins (> 40% to sex hormone binding globulin, SHBG, and> 50% to albumin).
Levonorgestrel at a dose of 1.5 mg is excreted in milk in insignificant amounts (Sandoz 2016, Gainer 2007) and no adverse effects have been observed in the short or long term in infants or breastfeeding (Shaaban 2019, Polakow 2013, FDA 2009).
Although the manufacturer (Sandoz 2016) and some authors (Gainer 2007) advise an interruption of breastfeeding for about 8 hours after taking the medication, the small amount excreted in milk does not justify this interruption and other expert authors state that no breastfeeding interruption is required after taking levonorgestrel as an emergency contraceptive (Polakow 2013,, FFPRHC 2004).
Progestogens do not affect breastfeeding or the infant.
Several medical associations and expert consensus consider the use of levonorgestrel as an emergency contraceptive during breastfeeding to be safe and unrestricted (CDC 2016, Jatlaoui 2016, Berens (ABM) 2015, WHO / OMS 2015, Polakow 2013, Shaaban 2013, FFPRHC 2004).
List of essential medicines WHO: compatible with breastfeeding (WHO 2002).
American Academy of Pediatrics: medication usually compatible with breastfeeding (AAP 2001).
We do not have alternatives for (-)-13β-Ethyl-17β-hydroxy-18,19-dinor-17α-pregn-4-en-20-yn-3-one since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.
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