Last update: March 22, 2018
Not risky for breastfeeding or infant.
Excretion into breast milk is very unlikely since absorption through skin, vaginal mucosa, and, even intestinal mucosa into plasma is very poor with non-significant plasma levels or below the detection threshold (<10 ng/mL). In addition, because of a high plasma protein binding capacity, excretion into breast milk seems to be less likely.
It is used frequently for treatment of Candida infection, either in skin or mouth mucosa, even in newborn and premature infants without observed side-effects.
In case of use on the nipple, do it after feeding the baby and cleanse thoroughly the surface before the next one.
Do not use creams, gels and other locally applied products that contain paraffin (mineral oil) to prevent absorption by the infant.
We do not have alternatives for 1-(α-2-Chlorotrityl)imidazole since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.
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